Project: Addressing Health Disparities in HIV/AIDS Clinical Trials (ACT Project)
Funding Agency: National Institute of Allergy and Infectious Diseases
Principal Investigator: Marya Gwadz, Ph.D. & Noelle Leonard, Ph.D., CDUHR Co-Investigators (D. Mildvan, PI)
Study Participants: HIV+ African-Americans and Latinos
Objective: Determine individual and structural barriers to participation in AIDS clinical trials

Project: Applying Web Technology to Buprenorphine Treatment
Funding Agency: National Institute on Drug Abuse
Principal Investigator: Lisa A. Marsch, Ph.D.
Study Participants: Not Applicable
Objective: Develop an interactive, web-based patient education system for opioid-dependent individuals in office-based buprenorphine treatment

Project: Collaborative Injection Drug Users Study III: Drug User Intervention Trial (CIDUS/DUIT)
Funding Agency: Centers for Disease Control and Prevention
Principal Investigator: Holly Hagan, Ph.D. (Seattle PI)
Study Participants: Young and new IDUs
Objective: Evaluate a peer-volunteer activism intervention to reduce risk behavior and HIV and HCV incidence

Project: Computer-Assisted HIV Prevention for Young Drug Users
Funding Agency: National Institute on Drug Abuse
Principal Investigator: Lisa A. Marsch, Ph.D.
Study Participants: Adolescents and young adults
Objective: Evaluate an interactive, computer-assisted HIV, STD and disease prevention program

Project: Contextual Influences on Sexual Risk among Latino MSM
Funding Agency: National Institute of Child Health and Human Development
Principal Investigator: Michele G. Shedlin, Ph.D., CDUHR Co-Investigator (M.C. Zea, PI)
Study Participants: Dominican, Columbian and Brazilian MSM
Objective: Explore sociocultural, psychosocial and contextual influences on unprotected sex

Project: Couples HIV Intervention Randomized Controlled Trial (CHIP)
Funding Agency: National Institute on Drug Abuse
Principal Investigator: James M. McMahon, Ph.D.
Study Participants: Women drug users and their main male sex partner
Objective: Develop and evaluate a couples, relationship-based intervention

Project: Cross-Border HIV Prevention Project: China and Vietnam
Funding Agency: National Institute on Drug Abuse
Principal Investigator: Don C. Des Jarlais, Ph.D., CDUHR Co-Investigator (T. Hammett, PI)
Study Participants: IDUs and community leaders
Objective: Implement HIV prevention program and assess control of HIV transmission

Project: Drug Use and HIV Risk in Nicaragua (NICA Project)
Funding Agency: National Institute on Drug Abuse
Principal Investigator: Michele G. Shedlin, Ph.D.
Study Participants: Drug users
Objective: Determine drug use patterns, and identify methods of reaching drug using populations; develop institutional capacity to conduct behavioral research in drug use and HIV

Project: Etiology and Prevention of HCV in IDUs (SPIN Project)
Funding Agency: National Institute on Drug Abuse
Principal Investigator: Holly Hagan, Ph.D.
Study Participants: HCV-negative IDUs
Objective: Study etiologic risk factors for HCV. Evaluate changes in syringe exchange programs and partner notification on HCV

Project: Evaluation of Implementation of Harm Reduction Services in MMTP
Funding Agency: amfAR and NYC Department of Health & Mental Hygiene
Principal Investigator: Naomi Braine, Ph.D.
Study Participants: MMTP clients
Objective: Examine the organizational process of introducing harm reduction services in an MMTP and assess outcomes among clients

Project: Expanded Syringe Access Program: NY Evaluation (ESAP)
Funding Agency: National Institute on Drug Abuse
Principal Investigator: Sherry Deren, Ph.D. & Don C. Des Jarlais, Ph.D., CDUHR Co-Investigators (D. Vlahov, PI)
Study Participants: IDUs
Objective: Assess the effectiveness of the NYS Expanded Syringe Access Demonstration Program

Project: HIV Risk and Substance Use in Adolescent Couples
Funding Agency: National Institute on Drug Abuse
Principal Investigator: Noelle R. Leonard, Ph.D.
Study Participants: Adolescent couples
Objective: Identify individual and dyadic factors that influence sexual risk behavior; develop and pilot an intervention for adolescent couples

Project: Interventions for HIV-Positive Mothers with Drinking Problems (Family First)
Funding Agency: National Institute on Alcohol Abuse and Alcoholism
Principal Investigator: Marya Gwadz, Ph.D.
Study Participants: HIV+ mothers and their adolescent children
Objective: Design, implement and evaluate a 14-session intervention to reduce substance use risk and enhance parenting

Project: Measuring HIV/AIDS Knowledge among the Deaf (DEAF AIDS)
Funding Agency: National Institute of Mental Health
Principal Investigator: Marjorie F. Goldstein, Ph.D.
Study Participants: Deaf individuals
Objective: Develop an HIV/AIDS-related knowledge, attitudes and risk behavior survey which is self-administered on computer

Project: MSM Communities in NYC Respond to HIV and Methamphetamine
Funding Agency: National Institute on Drug Abuse
Principal Investigator: Naomi Braine, Ph.D.
Study Participants: MSM and community stakeholders
Objective: Explore community response to methamphetamine use and HIV-related risk behavior among MSM

Project: National HIV Behavioral Surveillance Among High Risk Heterosexuals: New York City
Funding Agency: CDC through the New York City Department of Health and Mental Hygiene
Principal Investigator: Holly Hagan, Ph.D.
Study Participants: Heterosexual men and women living in high HIV risk neighborhoods
Objective: Identify high HIV risk neighborhoods, document HIV-related risk behavior and conduct HIV testing

Project: National HIV Behavioral Surveillance Among Injection Drug Users: New York City
Funding Agency: CDC through the New York City Department of Health and Mental Hygiene
Principal Investigator: Holly Hagan, Ph.D.
Study Participants: IDUs
Objective: Examine the current state of the IDU community in New York City

Project: National Study of Syringe Exchange Programs
Funding Agency: National Institute on Drug Abuse
Principal Investigator: Don C. Des Jarlais, Ph.D.
Study Participants: Syringe Exchange Programs (SEPs)
Objective: Assess SEPs and identify individual factors associated with continued risk

Project: Networks, Norms and HIV/STI Risk Among Youth (NNAHRAY)
Funding Agency: National Institute on Drug Abuse
Principal Investigator: Samuel R. Friedman, Ph.D.
Study Participants: Young adults and IDUs
Objective: Determine how network characteristics, norms, behaviors and infections are

Project: New Hispanic Communities and HIV Risk (New Communities)
Funding Agency: National Institute of Child Health and Human Development
Principal Investigator: Michele G. Shedlin, Ph.D.
Study Participants: New Hispanic immigrants
Objective: Examine the cultural factors that influence HIV risk and the environmental contexts for risk and protective behaviors

Project: Recent Changes in HIV Testing Recommendations: Impact on Youth at Risk
Funding Agency: The Foundation for AIDS Research (amfAR)
Principal Investigator: Marya Viorst Gwadz, Ph.D.
Study Participants: Homeless youth
Objective: Describe influences that impede or facilitate HIV testing and access to care

Project: Science of Addiction for Deaf High School Students - Phase I
Funding Agency: National Institute on Drug Abuse
Principal Investigator: Marjorie F. Goldstein, Ph.D.
Study Participants: Deaf high school and college students; teachers of the deaf
Objective: Adapt and translate for Deaf high school students, sections of the NIDA curriculum - The Brain: Understanding Neurobiology through the Study of Addiction

Project: STOP Hep C - Outpatient
Funding Agency: Josiah Macy, Jr. Foundation
Principal Investigator: Shiela M. Strauss, Ph.D.
Study Participants: Clinical and medical staff at outpatient drug treatment programs
Objective: Implement and evaluate training to increase knowledge regarding the HCV epidemic among drug users

Project: Study to Reduce Intravenous Exposures (STRIVE)
Funding Agency: National Institute on Drug Abuse
Principal Investigator: Holly Hagan, Ph.D. (Seattle PI)
Study Participants: HCV+ IDUs
Objective: Evaluate a peer-volunteer activism intervention and identify those willing and eligible to undergo HCV treatment

Project: Synthesis: HCV Epidemiology and Prevention in Drug Users
Funding Agency: National Institute on Drug Abuse
Principal Investigator: Holly Hagan, Ph.D.
Study Participants: Not applicable
Objective: Meta-analysis of studies on HCV prevalence and incidence among drug users

Project: Treatment Engagement of HIV Positive Heroin Users (TREND)
Funding Agency: Substance Abuse and Mental Health Services Administration, Center for Substance Abuse Treatment
Principal Investigator: Marjorie F. Goldstein, Ph.D.
Study Participants: HIV+ heroin users
Objective: Evaluate intensive vs. brief counseling intervention by assessing engagement in medical care and drug treatment

Project: UAB-NDRI-Substance Abuse ICOHRTA in Ukraine
Funding Agency: Fogarty International Center
Principal Investigator: Sherry Deren, Ph.D. & Samuel R. Friedman, Ph.D., CDUHR Co-Directors (S. Vermund, PI)
Study Participants: Not applicable
Objective: Train students from the Ukraine on HIV/drug use issues. Students earn MPH at UAB and do internship with CDUHR

Project: Women Drug Users, Their Male Partners and HIV Risk (CAR Project)
Funding Agency: National Institute on Drug Abuse
Principal Investigator: Stephanie Tortu, Ph.D.
Study Participants: Women drug users and their main male sex partner
Objective: Examine effect of relationship characteristics, drug use and situation variables on HIV risk behavior in couples